As the UEFA Europa Conference League 2024/25 unfolds, the clash between Real Betis and Vitoria Guimaraes in the Round of 16 promises to be a captivating encounter. Real Betis comes into this match with a point to prove, especially after their recent victory against the formidable Real Madrid. For Vitoria Guimaraes, this match represents a golden opportunity to punch above their weight and advance further in European competition.
| ℹ️ Tournament | UEFA Europa Conference League 2024/25 |
|---|---|
| ⚽️ Venue | Benito Villamarin |
| 🗓️ Date | 06.03.2025 |
| ⏰ Time | 19:45 CEST |
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Real Betis vs Vitoria Guimaraes prediction: Real Betis moneyline
Real Betis, known for their aggressive gameplay, has shown a penchant for ball control and incisive attacking movements. Their disciplined approach is reflected in their relatively low number of fouls and high pass accuracy of 66%. In contrast, Vitoria Guimaraes has a more cautious style, evident from their higher foul count and a slightly lower pass accuracy of 55%. These dynamics suggest Real Betis might dominate possession, putting them in a favorable position to capitalize on scoring opportunities.
| 🔥Hot Tip | Real Betis to win with odds higher than ~1.5 |
|---|---|
| ⚽Correct Score | 2-0 in favor of Real Betis |
| 💥Both Teams To Score | No |
| 🎯Total Goals Over 2.5 | Yes |
Team Analysis
Real Betis has showcased a rollercoaster of performance levels in recent matches. However, their last two victories, including a 2-1 win over Real Madrid, highlight their capacity to outplay strong opponents.
Vitoria Guimaraes, despite their unbeaten streak in the last five matches, has faced moderately challenging opponents compared to Real Betis’ lineup. Their 0-0 stalemate with Braga and a 1-1 draw with Porto suggest that while they possess resilience, they may struggle to penetrate Betis’s defenses effectively.
Most recent H2Hs: Real Betis dominates
| Team | Goals | Total Shots | Pass Accuracy (%) | Interceptions | Offsides | Total Fouls | Total Corners |
|---|---|---|---|---|---|---|---|
| Real Betis | 10 | 89 | 66% | 42 | 4 | 4 | 33 |
| Vitoria Guimaraes | 2 | 52 | 55% | 30 | 13 | 1 | 32 |
🚨Read our full Real Betis vs Vitoria Guimaraes stats for more analysis.

Vitoria Guimaraes. Source: Official Website
Pre-game odds and win probability: Real Betis the favourite
| Bookmaker | Real Betis | Draw | Vitoria Guimaraes |
|---|---|---|---|
| 22bet | 1.54 | 3.84 | 6.85 |
| spinbetter | 1.57 | 3.91 | 6.97 |
| betonred | 1.56 | 3.90 | 6.40 |
You can find all our predictions for today’s games on our football betting tips page.
Key Players to Watch
Isco from Real Betis is in scintillating form, with three goals and two assists in his last five outings. His ability to dictate play in the midfield, combined with his sharp eye for goal, makes him a pivotal figure in Real Betis’s lineup. For Vitoria Guimaraes, Úmaro Embaló has been a beacon of hope, contributing two crucial goals in recent matches. His agility and stroke of aggression could pose a challenge for Betis’s backline.
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Possible Starting Lineup
Both teams are likely to start with a 4-2-3-1 formation, reflecting their recent tactics.

For Real Betis, the midfield duo of Isco and Johnny Cardoso will aim to control the game tempo, while Antony Matheus dos Santos is expected to lead the attacking front.
Vitoria Guimaraes may rely on the defensive solidity provided by Mikel Villanueva and the creative exploits of Tiago Silva in the midfield. The pressure will be immense, and both managers will likely opt for their trusted lineups to secure a spot in the next phase.
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Real Betis. Source: Official Website
The Verdict
My main pick is Real Betis to win. Their recent performances against high-caliber teams and the significant skill gulf should give them the edge over Vitoria Guimaraes. With Isco spearheading their attack and their ability to adapt to various game situations, Real Betis stands as the more prepared side to triumph in this encounter.

