As the 2024/25 Serie A season approaches its crucial spring juncture, Genoa and Lazio are set for a showdown at Luigi Ferraris that could prove decisive—not for the Scudetto race, but for either side’s ambitions. With Genoa entrenched in mid-table and Lazio sniffing at European dreams, points here matter differently for each. For Patrick Vieira’s Genoa, this is a chance to test mettle against a top-seven side, while Lazio, guided by Marco Baroni, cannot afford missteps in a crowded chase for Europe. Intrinsically, both teams come here seeking to define their identity in a campaign marked by fluctuating form. The stakes? Critical for momentum, even if not strictly for survival or title glory.
| 🏆 Tournament: | Serie A 2024/25 (Regular Season) |
| 🏟 Venue: | Luigi Ferraris, Genova |
| 🗓️ Date: | 21.04.2025 |
| ⏰ Time: | 19:00 CEST |
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Genoa vs Lazio prediction
Lazio enters as a clear favourite, not just by bookmakers’ consensus (42% win probability), but given their sharper attacking edge and higher league standing. Genoa’s recent form is patchy (one win in four, struggling to find goals), and their attack has looked sterile against resolute sides. In contrast, Lazio has navigated a demanding schedule with resilience—taking points off tough rivals and boasting a five-goal surge across their recent five matches. Still, their penchant for conceding (43 goals) balances their attacking flair, often inviting tense finishes.
Statistically, Lazio’s looser approach—more fouls (54 in last 5), more yellow cards (15), yet dynamic pressing (60 interceptions)—suggests an open contest. Genoa, notably more composed in discipline but lacking bite up front (just 1 goal in last 5 matches), seems set to play a conservative 3-4-2-1, sitting deep and probing on the break.
Given these metrics, the best bet shapes up as a Lazio win with an Asian Handicap (-0.5), or a Draw No Bet on Lazio for risk-averse backers. The expected goals tally leans under, as Genoa’s home fixtures have averaged less than 2.5 goals, and their solidity at home could frustrate the Romans.
| 🔥Hot Tip: | Lazio Asian Handicap -0.5 |
| ⚽Total Goals: | Under 2.5 goals |
| 💥Both Teams To Score: | No |
| 🎯Total Corners: | Over 8.5 corners |
Team Analysis
Genoa recent games: Genoa’s last fixture saw them huff and puff to a 0-0 draw against Verona, underlining their ongoing attacking woes. Even their win against Udinese (1-0) was less a show of dominance, more of disciplined defending and opportunistic finishing. Against Juventus, they fell narrowly, 0-1, though the defence kept the margin respectable. The 2-1 triumph over Lecce highlighted rare clinical edge, but over the past five, goals have dried up.
Lazio recent games: Conversely, Lazio’s 2-0 win over Bodo Glimt in Europe showcased their multiple attacking vectors and pressing work-rate. Their 1-1 Derby della Capitale draw with Roma revealed a disciplined, if not ruthless, approach—holding their nerve amid the furor. They do, however, oscillate: the 0-2 European stumble (again vs Bodo Glimt) exposed defensive lapses, but bounces back with a gritty 1-0 display over Atalanta. They are less static, more proactive—a double-edged sword that can both open matches up and leave gaps.
Most recent H2Hs: Lazio dominates
| Statistic | Genoa | Lazio |
|---|---|---|
| Total shots | 6 | 14 |
| Free kicks | 10 | 14 |
| Corner kicks | 3 | 8 |
| Total fouls | 14 | 19 |
| Pass accuracy (%) | 75% | 81% |
| Interceptions | 17 | 24 |
🚨Read our full Genoa vs Lazio stats for more analysis.
Pre-game odds and win probability: Lazio the favourite
| Moneyline | Genoa 3.29-3.56 | Lazio 2.18-2.38 | |
|---|---|---|
| Draw | 3.05-3.20 | |
| Over/Under | Over 2.5 2.15 | Under 2.5 1.75 | |
| BTTS (both teams to score) | Yes 1.80 | No 2.10 | |
The odds strongly reflect Lazio’s slightly superior squad depth and away form; the gap isn’t unbridgeable, but with Genoa’s one-goal attack, bookmakers judge a disciplined Lazio more likely to take three points. The draw commands serious respect, hinting at Genoa’s defensive resilience in this fortress, but market consensus still tilts blue-and-white.
You can find all our predictions for today’s games on our football betting tips page.
Key Players to Watch
Genoa: Andrea Pinamonti – The forward, though currently short of goals, has been Genoa’s most persistent attacking outlet, leading the line with strength and intelligent hold-up play. He’s managed the most shots (5) in the last five appearances and, if Genoa are to breach Lazio’s rearguard, he is the likeliest culprit. His presence enables the wingbacks to push up and overload wide areas—very much in Vieira’s tactical wheelhouse.
Lazio: Mattia Zaccagni – Not Lazio’s top scorer this season, but Zaccagni is the metronome on the flank. Across five matches, his trickery and movement created key opportunities (10 shots, 3 yellow cards won), while his pass volume and relentless pressing have been pivotal. In a team with an abundance of technical quality, Zaccagni stands out for his unpredictability and work rate.
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Possible Starting Lineups

Genoa possible starting eleven
- GK: Nicola Leali
- DF: Johan Vásquez, Koni De Winter, Alessandro Zanoli
- MF: Stefano Sabelli, Morten Thorsby, Patrizio Masini, Aarón Martin Caricol
- MF: Morten Wetche Frendrup, Fabio Miretti
- FW: Andrea Pinamonti
Genoa will likely persist with the 3-4-2-1, utilizing Vásquez and De Winter’s ball-playing attributes at the back. Sabelli and Martin provide thrust out wide, hoping to carve out rare chances for the lone striker, Pinamonti. Keep an eye on Masini and Miretti—young, dynamic, if inconsistent, they must establish a midfield foothold to prevent Lazio from flooding middle zones.
Lazio possible starting eleven
- GK: Ivan Provedel
- DF: Adam Marušić, Mario Gila, Alessio Romagnoli, Elseid Hysaj
- MF: Mattéo Guendouzi, Nicolò Rovella
- MF: Gustav Isaksen, Mattia Zaccagni, Pedro
- FW: Valentin Castellanos
Baroni’s Lazio lean into a 4-2-3-1, with fullbacks pressing high and wingers (Isaksen, Zaccagni) driving technical creativity. Guendouzi and Rovella control tempo at the base, while Castellanos—mobile and opportunistic—looks to exploit gaps left by Genoa’s wide setup. Defensive rotations mean stability, but Zaccagni and Marušić are key this time for transitions and width.
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Lazio. Source: Official Facebook. Edited photo
The Verdict
Momentum and quality roll with Lazio—statistically and tactically. Genoa will battle, as is the Russian sporting spirit (дух борьбы!), and under Vieira’s stewardship they remain compact and hard to break down at Luigi Ferraris. Still, goalscoring remains a persistent Achilles heel, and the visitors’ greater technical and creative options should dictate play.
Main pick: Lazio to win (Asian Handicap -0.5). Expect a narrow, hard-fought away victory (0-1 or 0-2), with Genoa’s defensive grit just enough to frustrate, but probably not enough to deny Lazio’s European chase another three points. For punters, the under 2.5 goals & “no” on BTTS offer value, given trends and lineup realities.